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Jeff Edwards

Professor
Physiology & Developmental Biology

3046 LSB
Provo, UT 84602

Biography

Research Interests


Learning and Memory as well as Reward/Addiction pathways- Using electrophysiology in combination with pharmacology and molecular biology techniques the lab studies synaptic plasticity, the cellular mechanism allowing our brains to learn and adapt. We study synaptic plasticity in the hippocampus, the primary region involved in learning and memory and the ventral tegmental area, which is the reward pathway of the brain. The goal is to understand normal brain function and as a result apply this to abnormal states such as epilepsy and Alzheimer’s in the hippocampus and addiction in the ventral tegmental area.

Experience

Academic - Post-Secondary

  • Associate Director, BYU Neuroscience Center, 2015-Present
  • Faculty, BYU Neuroscience Center, 2007-Present
  • Full Professor, Brigham Young University, -2018
  • Associate Professor, Brigham Young University, 2013-2018

Professional

  • President, Society for Neuroscience Intermountain Branch, 2012-2015

Memberships

  • International Cannabinoid Research Society, 2012-Present
  • American Association for the Advancement of Science, 2007-Present
  • Neuroscience Center, 2007-Present
  • Society for Neuroscience, 2004-Present
  • Intermountain Chapter Society for Neuroscience, 2000-Present
  • American Physiological Society, 1998-Present
  • Idaho Academy of Sciences, 2005-2006
  • Association for Chemoreception Sciences, 1999-2004

Honors and Awards

  • Brigham Young University : Graduate Mentoring Award
  • PDBio : PDBio Award for Outstanding Achievement and Service
  • Faculty for Undergraduate Neuroscience : Honors Award
  • Faculty for Undergraduate Neuroscience : Honors Award
  • Brigham Young University : Graduate Mentoring Award
  • Faculty for Undergraduate Neuroscience : Honors Award
  • Faculty Center : Course Development Project Grant
  • BYU-Idaho : Thomas E. Ricks Award
  • NIH : National Service Research Award- Postdoctoral Fellowship
  • Association for Chemoreception Sciences : Don Tucker Memorial Award Nominee
  • Assocation for Chemoreception Sciences : Assocation for Chemoreception Sciences Travel Awards
  • Association for Chemoreception Sciences : Don Tucker Memorial Award Nominee
  • Intermountain Chapter Society for Neuroscience : Most outstanding presentation

Courses Taught

Winter 2019

  • NEURO 449R: Neuro Research Experience Section 006
  • PDBIO 295R: Introductory Undgrad Research Section 005
  • PDBIO 349R: PDBio Teaching Experience Section 006
  • PDBIO 362: Advanced Physiology Section 002, 003
  • PDBIO 495R: Adv Undergraduate Research Section 005
  • PDBIO 550R: Advanced Topics in PDBio Section 006
  • PDBIO 649R: Laboratory Research Section 005
  • PDBIO 689R: Practicum LfSci Tchg or Resrch Section 001

Fall 2018

  • NEURO 449R: Neuro Research Experience Section 005
  • PDBIO 295R: Introductory Undgrad Research Section 005
  • PDBIO 495R: Adv Undergraduate Research Section 005
  • PDBIO 568: Biophysics Section 001
  • PDBIO 601: Cell & Molecular Physiology Section 001
  • PDBIO 649R: Laboratory Research Section 005

Summer 2018

  • NEURO 449R: Neuro Research Experience Section 006

Spring 2018

  • NEURO 449R: Neuro Research Experience Section 006
  • NEURO 799R: Doctoral Dissertation Section 003
  • PDBIO 295R: Introductory Undgrad Research Section 005
  • PDBIO 495R: Adv Undgraduate Research Section 005

Research Interests

Learning and Memory as well as Reward/Addiction pathways- Using electrophysiology in combination with pharmacology and molecular biology techniques the lab studies synaptic plasticity, the cellular mechanism allowing our brains to learn and adapt. We study synaptic plasticity in the hippocampus, the primary region involved in learning and memory and the ventral tegmental area, which is the reward pathway of the brain. The goal is to understand normal brain function and as a result apply this to abnormal states such as epilepsy and Alzheimer’s in the hippocampus and addiction in the ventral tegmental area.

Honors and Awards

  • BYU Phi Kappa Phi Distinguished Faculty Lecturer Award
  • Graduate Mentoring Award
  • PDBio Award for Outstanding Achievement and Service
  • Honors Award
  • Honors Award
  • Graduate Mentoring Award
  • Honors Award
  • Course Development Project Grant
  • Thomas E. Ricks Award
  • National Service Research Award- Postdoctoral Fellowship
  • Don Tucker Memorial Award Nominee
  • Assocation for Chemoreception Sciences Travel Awards
  • Don Tucker Memorial Award Nominee
  • Most outstanding presentation

Memberships

  • International Cannabinoid Research Society: ( - Present)
  • American Association for the Advancement of Science: ( - Present)
  • Neuroscience Center: ( - Present)
  • Society for Neuroscience: ( - Present)
  • Intermountain Chapter Society for Neuroscience: ( - Present)
  • American Physiological Society: ( - Present)
  • Idaho Academy of Sciences: ( - Present)
  • Association for Chemoreception Sciences: ( - Present)

Professional Citizenship

  • Editor, Associate Editor, Frontiers in Neuroscience, 2020-06-01 - 2020-06-30 - Present
  • Editorial Review Board Member, Frontiers in Synaptic Neuroscience, 2019-01-01 - 2019-12-31 - Present
  • Reviewer, Ad Hoc Reviewer, Journal Reviewer, 2019-01-01 - 2019-01-31 - Present
  • Editor, Associate Editor, BMC Neuroscience, 2017-01-01 - 2017-12-31 - Present
  • Editor, Associate Editor, Scientific Reports (a Nature Publishing Group journal), 2015-01-01 - 2015-12-31 - Present
  • Publications-outreach, New York University, - 2020-09-01 - 2020-09-30
  • Grant Proposal Reviewer, External, Tobacco-Related Disease Research Program (TRDRP), - 2020-04-01 - 2020-04-30
  • Committee/Council Member, National Research Center (CNR) of Italy, 2019-07-01 - 2019-07-31 - 2019-12-01 - 2019-12-31
  • Reviewer, Ad Hoc Reviewer, National Science Centre , - 2019-03-01 - 2019-03-31
  • Grant Proposal Reviewer, External, Tobacco-Related Disease Research Program (TRDRP) , - 2018-12-01 - 2018-12-31
  • Media Interview, BYU-Idaho Radio, - 2018-01-01 - 2018-12-31
  • Media Interview, KSL TV, - 2018-01-01 - 2018-12-31
  • Reviewer, Ad Hoc Reviewer, Scientific Journal/book Reviewer, 2018-01-01 - 2018-01-31 - 2018-12-01 - 2018-12-31
  • Media Interview, Various Media interviews: Men's Health, BYU News, KUTV news, etc., - 2018-01-01 - 2018-12-31
  • Media Interview, Canadian Broadcast Corporation, - 2018-10-01 - 2018-10-31
  • Grant Proposal Reviewer, External, National Institute of Health, - 2018-07-01 - 2018-07-31
  • Conference-Related Role, Spring Brain Conference, - 2018-04-01 - 2018-04-30
  • Grant Proposal Reviewer, External, Tobacco-Related Disease Research Program (TRDRP), - 2018-03-01 - 2018-03-31
  • Media Interview, New York Times, - 2018-02-01 - 2018-02-28
  • Reviewer, Ad Hoc Reviewer, Scientiific Journal Reviewer, 2017-01-01 - 2017-01-31 - 2017-12-01 - 2017-12-31
  • Media Interview, BYU Radio Top of Mind Interview, - 2017-10-01 - 2017-10-31
  • Media Interview, KBYU Channel 11 Interview, - 2017-10-01 - 2017-10-31
  • Media Interview, National Press Interviews, - 2017-10-01 - 2017-10-31
  • Conference-Related Role, Spring Brain Conference, 2015-06-01 - 2015-06-30 - 2017-04-01 - 2017-04-30
  • Reviewer, Ad Hoc Reviewer, Many professional journals, 2016-01-01 - 2016-01-31 - 2016-12-01 - 2016-12-31
  • Grant Proposal Reviewer, External, Medical Research Council- MRC (Britains equivalent of NIH), - 2016-07-01 - 2016-07-31
  • Other, Nebo School Distric, - 2015-12-01 - 2015-12-31
  • Reviewer, Ad Hoc Reviewer, J Neuroscience, J Neurophysiology, Neuroscience, Neuroscience letters, etc. , 2015-01-01 - 2015-01-31 - 2015-12-01 - 2015-12-31
  • Editorial Review Board Member, Nature Publishing Group, 2014-01-01 - 2014-12-31 - 2015-01-01 - 2015-12-31
  • Grant Proposal Reviewer, External, National Institute of Health, - 2015-10-01 - 2015-10-31
  • Media Interview, Top of Mind Radio Broadcast, - 2015-08-01 - 2015-08-31
  • Officer (specify in Other), Society for Neuroscience Intermountain Branch, 2012-04-01 - 2012-04-30 - 2015-06-01 - 2015-06-30
  • Reviewer, Ad Hoc Reviewer, McGraw Hill Publishing, - 2015-04-01 - 2015-04-30
  • Reviewer, Ad Hoc Reviewer, Pflugers Archiv., J Neurophys, Neuroscience, Neuroscience Letters, Neurochemistry Int, etc. , 2013-01-01 - 2013-12-31 - 2014-01-01 - 2014-12-31
  • Reviewer, Ad Hoc Reviewer, Journal of Neuroscience, 2012-09-01 - 2012-09-30 - 2014-01-01 - 2014-12-31
  • Officer, Utah County Delegate, 2012-05-01 - 2012-05-31 - 2014-01-01 - 2014-12-31
  • Reviewer, Ad Hoc Reviewer, Neuroscience Letters, 2012-03-01 - 2012-03-31 - 2014-01-01 - 2014-12-31
  • Conference-Related Role, Intermountain Society for Neuroscience Branch, 2012-11-01 - 2012-11-30 - 2014-11-01 - 2014-11-30
  • Other, Intermountain SfN Branch Poster Session, 2013-10-01 - 2013-10-31 - 2014-10-01 - 2014-10-31
  • Reviewer, Ad Hoc Reviewer, National Conference on Undergraduate Research Journal, 2012-03-01 - 2012-03-31 - 2013-01-01 - 2013-12-31
  • Other, Intermoutain Graduate Research Sympsium, 2012-04-01 - 2012-04-30 - 2012-04-01 - 2012-04-30
  • Media Interview, , - 2011-12-01 - 2011-12-31
  • Reviewer, Ad Hoc Reviewer, Pharmacological Reports, - 2011-01-01 - 2011-12-31
  • Reviewer, Ad Hoc Reviewer, Pharmacological Research, - 2011-01-01 - 2011-12-31
  • Other, , - 2011-04-01 - 2011-04-30
  • Other, Intermountain Graduate Research Symposium, - 2010-06-01 - 2010-06-30
  • Other, LIfe Science Poster Presentation, - 2010-03-01 - 2010-03-31
  • Other, Society for Neuroscience- Brain Awareness Week, - 2010-03-01 - 2010-03-31
  • Other, Society for Neuroscience, - 2010-01-01 - 2010-01-31

Courses Taught

2020

  • PDBIO 495R: Section 004
  • PDBIO 550R: Section 006
  • PDBIO 568 : Section 001
  • PDBIO 799R: Section 004
  • PDBIO 295R: Section 004
  • NEURO 649R: Section 008
  • PDBIO 649R: Section 004
  • NEURO 449R: Section 004
  • PDBIO 799R: Section 005
  • PDBIO 295R: Section 005
  • NEURO 449R: Section 003
  • PDBIO 799R: Section 005
  • PDBIO 295R: Section 005
  • PDBIO 495R: Section 005
  • PDBIO 362 : Section 002
  • PDBIO 799R: Section 005
  • PDBIO 295R: Section 005
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 005

2019

  • PDBIO 495R: Section 005
  • PDBIO 568 : Section 001
  • PDBIO 799R: Section 005
  • PDBIO 295R: Section 005
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 004
  • PDBIO 495R: Section 005
  • PDBIO 799R: Section 005
  • PDBIO 495R: Section 005
  • PDBIO 799R: Section 005
  • PDBIO 295R: Section 005
  • NEURO 449R: Section 005
  • PDBIO 495R: Section 005
  • PDBIO 362 : Section 002
  • PDBIO 362 : Section 003
  • PDBIO 550R: Section 006
  • PDBIO 295R: Section 005
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 006
  • PDBIO 349R: Section 006
  • PDBIO 689R: Section 001

2018

  • PDBIO 495R: Section 005
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 295R: Section 005
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 005
  • NEURO 449R: Section 006
  • PDBIO 495R: Section 005
  • NEURO 799R: Section 003
  • PDBIO 295R: Section 005
  • NEURO 449R: Section 006
  • PDBIO 495R: Section 005
  • PDBIO 362 : Section 002
  • NEURO 799R: Section 005
  • PDBIO 305 : Section 004
  • PDBIO 295R: Section 005
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 006

2017

  • PDBIO 495R: Section 006
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 5
  • NEURO 799R: Section 7
  • PDBIO 305 : Section 004
  • PDBIO 295R: Section 006
  • PDBIO 649R: Section 6
  • NEURO 449R: Section 005
  • PDBIO 495R: Section 6
  • PDBIO 799R: Section 3
  • NEURO 799R: Section 3
  • NEURO 449R: Section 6
  • PDBIO 799R: Section 4
  • NEURO 799R: Section 3
  • NEURO 449R: Section 6
  • PDBIO 494R: Section 6
  • PDBIO 362 : Section 002
  • PDBIO 362 : Section 003
  • PDBIO 550R: Section 008
  • PDBIO 799R: Section 6
  • NEURO 799R: Section 5
  • PDBIO 649R: Section 6
  • NEURO 449R: Section 6
  • PDBIO 494R: Section 006

2016

  • PDBIO 495R: Section 6
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 5
  • NEURO 799R: Section 7
  • PDBIO 649R: Section 6
  • NEURO 449R: Section 005
  • PDBIO 799R: Section 3
  • NEURO 799R: Section 3
  • PDBIO 799R: Section 4
  • NEURO 799R: Section 3
  • PDBIO 495R: Section 006
  • PDBIO 362 : Section 002
  • PDBIO 799R: Section 6
  • NEURO 799R: Section 5
  • PDBIO 305 : Section 005
  • NEURO 649R: Section 2
  • NEURO 449R: Section 006
  • PDBIO 689R: Section 1
  • PDBIO 494R: Section 006

2015

  • PDBIO 495R: Section 007
  • PDBIO 568 : Section 001
  • PDBIO 601: Section 1
  • PDBIO 799R: Section 5
  • NEURO 799R: Section 7
  • NEURO 649R: Section 4
  • NEURO 449R: Section 006
  • PDBIO 494R: Section 008
  • PDBIO 799R: Section 013
  • NEURO 649R: Section 014
  • NEURO 449R: Section 033
  • PDBIO 494R: Section 028
  • PDBIO 799R: Section 004
  • NEURO 649R: Section 006
  • NEURO 449R: Section 007
  • PDBIO 495R: Section 007
  • PDBIO 362 : Section 002
  • PDBIO 362 : Section 003
  • PDBIO 799R: Section 007
  • NEURO 799R: Section 005
  • PDBIO 305 : Section 004
  • NEURO 649R: Section 002
  • NEURO 449R: Section 006
  • PDBIO 689R: Section 002
  • PDBIO 494R: Section 007

2014

  • PDBIO 495R: Section 007
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 006
  • NEURO 649R: Section 004
  • PDBIO 649R: Section 007
  • NEURO 449R: Section 006
  • PDBIO 799R: Section 012
  • NEURO 649R: Section 012
  • PDBIO 649R: Section 026
  • PDBIO 494R: Section 028
  • PDBIO 799R: Section 002
  • NEURO 649R: Section 006
  • PDBIO 649R: Section 007
  • NEURO 449R: Section 007
  • PDBIO 362 : Section 002
  • PDBIO 305 : Section 005
  • PDBIO 649R: Section 007
  • NEURO 449R: Section 007

2013

  • PDBIO 495R: Section 007
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 005
  • PDBIO 649R: Section 007
  • NEURO 699R: Section 004
  • NEURO 449R: Section 007
  • PDBIO 494R: Section 008
  • PDBIO 495R: Section 007
  • PDBIO 649R: Section 007
  • NEURO 449R: Section 007
  • PDBIO 649R: Section 007
  • NEURO 699R: Section 001
  • NEURO 449R: Section 007
  • PDBIO 495R: Section 007
  • PDBIO 799R: Section 003
  • PDBIO 305 : Section 005
  • PDBIO 305 : Section 007
  • NEURO 649R: Section 002
  • PDBIO 649R: Section 007
  • NEURO 449R: Section 007
  • PDBIO 349R: Section 008
  • PDBIO 650R: Section 002
  • PDBIO 494R: Section 007

2012

  • PDBIO 495R: Section 005
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 003
  • PDBIO 305 : Section 001
  • NEURO 649R: Section 004
  • PDBIO 649R: Section 005
  • PDBIO 699R: Section 005
  • NEURO 449R: Section 018
  • PDBIO 349R: Section 005
  • PDBIO 494R: Section 006
  • PDBIO 649R: Section 005
  • PDBIO 495R: Section 005
  • NEURO 649R: Section 006
  • PDBIO 649R: Section 005
  • NEURO 449R: Section 016
  • PDBIO 494R: Section 005
  • PDBIO 495R: Section 005
  • PDBIO 799R: Section 001
  • PDBIO 305 : Section 005
  • PDBIO 305 : Section 006
  • NEURO 649R: Section 002
  • PDBIO 649R: Section 005
  • NEURO 699R: Section 002
  • PDBIO 699R: Section 005
  • NEURO 449R: Section 006
  • PDBIO 494R: Section 005

2011

  • PDBIO 495R: Section 004
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 002
  • PDBIO 305 : Section 003
  • NEURO 649R: Section 004
  • PDBIO 649R: Section 004
  • PDBIO 699R: Section 004
  • NEURO 449R: Section 018
  • PDBIO 494R: Section 005
  • PDBIO 495R: Section 004
  • NEURO 649R: Section 006
  • PDBIO 649R: Section 004
  • PDBIO 699R: Section 006
  • NEURO 449R: Section 017
  • PDBIO 450R: Section 003
  • PDBIO 649R: Section 004
  • PDBIO 699R: Section 004
  • NEURO 449R: Section 017
  • PDBIO 495R: Section 004
  • PDBIO 799R: Section 005
  • PDBIO 305 : Section 005
  • PDBIO 305 : Section 007
  • NEURO 649R: Section 005
  • PDBIO 649R: Section 004
  • PDBIO 699R: Section 004
  • NEURO 449R: Section 017

2010

  • PDBIO 495R: Section 004
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 799R: Section 001
  • PDBIO 305 : Section 002
  • NEURO 649R: Section 005
  • PDBIO 649R: Section 004
  • PDBIO 699R: Section 004
  • NEURO 449R: Section 018
  • PDBIO 494R: Section 005
  • PDBIO 495R: Section 004
  • PDBIO 649R: Section 004
  • PDBIO 495R: Section 004
  • PDBIO 649R: Section 004
  • NEURO 449R: Section 017
  • PDBIO 495R: Section 004
  • PDBIO 550R: Section 008
  • PDBIO 305 : Section 006
  • PDBIO 305 : Section 007
  • PDBIO 649R: Section 004
  • NEURO 449R: Section 017
  • PDBIO 349R: Section 004
  • PDBIO 494R: Section 004

2009

  • PDBIO 495R: Section 004
  • NEURO 480: Section 1
  • PDBIO 568 : Section 001
  • PDBIO 601 : Section 001
  • PDBIO 305 : Section 002
  • PDBIO 305 : Section 006
  • PDBIO 649R: Section 003
  • NEURO 449R: Section 018
  • PDBIO 349R: Section 005
  • PDBIO 494R: Section 005
  • PDBIO 649R: Section 015
  • NEURO 449R: Section 017
  • PDBIO 494R: Section 004
  • PDBIO 495R: Section 004
  • PDBIO 550R: Section 001
  • PDBIO 649R: Section 004
  • NEURO 449R: Section 017
  • PDBIO 494R: Section 004
  • PDBIO 495R: Section 004
  • NEURO 480: Section 1
  • PDBIO 550R: Section 022
  • PDBIO 305 : Section 006
  • PDBIO 649R: Section 004
  • NEURO 449R: Section 018
  • PDBIO 349R: Section 004
  • PDBIO 650R: Section 004
  • PDBIO 494R: Section 004

2008

  • PDBIO 495R: Section 004
  • NEURO 480: Section 1
  • PDBIO 568 : Section 001
  • PDBIO 601: Section 1
  • PDBIO 305 : Section 002
  • PDBIO 649R: Section 003
  • NEURO 449R: Section 018
  • PDBIO 494R: Section 005
  • NEURO 449R: Section 017
  • PDBIO 495R: Section 004
  • PDBIO 495R: Section 004
  • NEURO 480: Section 1
  • PDBIO 305 : Section 004
  • NEURO 449R: Section 018
  • PDBIO 494R: Section 004

2007

  • PDBIO 495R: Section 004
  • NEURO 480: Section 1
  • PDBIO 601: Section 1
  • PDBIO 568: Section 1
  • NEURO 449R: Section 018
  • PDBIO 494R: Section 004
  • PDBIO 494R: Section 004
  • PDBIO 494R: Section 004
  • BIOL 494R: Section 046
  • PDBIO 494R: Section 018

Publications

  • Miller RM, Marriott D, Trotter J, Hammond T, Lyman D, Call T, Walker B, Christensen N, Haynie D, Badura Z, et alFebruary 9, 2018. Running exercise mitigates the negative consequences of chronic stress on dorsal hippocampal long-term potentiation in male mice.
  • Friend L, Weed J, Sandoval P, Nufer T, Ostlund I, Edwards JG. November 8, 2017. CB1-Dependent Long-Term Depression in Ventral Tegmental Area GABA Neurons: A Novel Target for Marijuana. 45th ed.
  • Steffensen SC, Shin SI, Nelson AC, Pistorius SS, Williams SB, Woodward TJ, Park HJ, Friend L, Gao M, Gao F, et alSeptember 13, 2017. α6 subunit-containing nicotinic receptors mediate low-dose ethanol effects on ventral tegmental area neurons and ethanol reward.
  • Hurst K, Badgley C, Ellsworth T, Bell S, Friend L, Prince B, Welch J, Cowan Z, Williamson R, Lyon C, et alSeptember 1, 2017. A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity. 9th ed.
  • Cordner RD, Friend LN, Mayo JL, Badgley C, Wallman A, Stallings CN, Young PL, Miles DR, Edwards JG, Bridgewater LC. April (2nd Quarter/Spring) 18, 2017. The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory.
  • Merrill CB, Friend LN, Newton ST, Hopkins ZH, Edwards JG. November 10, 2015. Ventral tegmental area dopamine and GABA neurons: Physiological properties and expression of mRNA for endocannabinoid biosynthetic elements.
  • Edwards JG. March, 2014. TRPV1 in the Central Nervous System: Synaptic Plasticity, Function, and Pharmacological Implications. VIIIth ed. Omar M.E., editor.
  • Taylor DH, Burman PN, Hansen DM, Wilcox RS, Larsen BR, Blanchard JK, Merrill CB, Edwards JG, Sudweeks SN, Wu J, et alApril (2nd Quarter/Spring), 2013. Nicotine enhances the excitability of GABA neurons in the ventral tegmental area via activation of alpha 7 nicotinic receptors on glutamate terminals.
  • Merrill C, McNeil M, Williamson R, Poole B, Nelson B, Sudweeks SN, Edwards JG. August, 2012. Identification of mRNA for endocannabinoid biosynthetic enzymes within hippocampal pyramidal cells and CA1 stratum radiatum interneuron subtypes using quantitative real-time polymerase chain reaction.
  • Jensen T, Edwards JG. January (1st Quarter/Winter), 2012. Calcineurin is required for TRPV1-induced long-term depression of hippocampal interneurons. 2nd ed.
  • Bennion D, Jensen T, Wallther C, Hamblin J, Wallmann A, Couch J, Blickenstaff J, Castle M, Dean L, Beckstead S, et alSeptember, 2011. Transient Receptor Potential Vanilloid 1 agonists modulate hippocampal CA1 LTP via the GABAergic system. 4th ed.
  • Steffensen SC, Bradley K, Hansen DM, Wilcox JD, Wilcox RS, Allison DW, Merrill CB, Edwards JG. December, 2010. The role of connexin-36 gap junctions in alcohol intoxication and consumption. 8th ed.
  • Edwards JG, Gibson H, Jensen T, Nugent F, Walther C, Blickenstaff J, Kauer J. November, 2010. A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons .
  • Wang Z, Edwards JG, Riley N, Provance DW, Karcher R, Li XD, Davison IG, Ikebe M, Mercer JA, Kauer JA, et alOctober (4th Quarter/Autumn), 2008. Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity.
  • Gibson HE, Edwards JG, Page RS, Hook MJV, Kauer JA. March, 2008. TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons.
  • Park M, Penick EC, Edwards JG, Kauer JA, Ehlers MD. September, 2004. Recycling Endosomes Supply AMPA Receptors for LTP.
  • Edwards JG, Michel WC. November, 2003. Pharmacological characterization of ionotropic glutamate receptors within the zebrafish olfactory bulb.

Presentations

  • Edwards JG, Boyce Z. Prophylactic Treatment of Post-Traumatic Stress Disorder with Mifepristone and Propranolol. Utah Conference of Undergraduate Education. February, 2020.
  • Edwards JG, Paskett L. The Effects of Cannabis on the Brain’s Reward System. Utah Conference of Undergraduate Education. February, 2020.
  • Edwards JG, Blaylock T. The Effects of the Ketogenic Diet on Learning and Memory. Utah Conference of Undergraduate Education. February, 2020.
  • Edwards JG, Winzenried E. True Prophylactic Treatment effect in a Rat PTSD Model on Synaptic Plasticity in Ventral Hippocampal and Lateral Amygdala. Utah Conference of Undergraduate Education. February, 2020.
  • Edwards JG, Bird D. Understanding Drug Addiction Pathways Through Optogenetics. Utah Conference of Undergraduate Education. February, 2020.
  • Edwards JG. The Brain’s Ability to Learn and Adapt: Stress, Exercise and Drugs . BYU Phi Kappa Phi Diestinguished Faculty Lecture. November, 2019.
  • Edwards JG, Winzenried E, Boyce Z, Neal E, Johnson T, Kimball S. Prophylatic treatment to prevent PTSD- Physiology, behavior and potential targets. Faculty for Undergraduate Neuroscience Symposium. October, 2019.
  • Edwards JG, Johnson T. Ketogenic diet effect on learning and memory. Snowbird Intermountain Society for Neuroscience Branch Symposium. October, 2019.
  • Edwards JG, Wu B. Acute & chronic cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Society for Neuroscience. October, 2019.
  • Edwards JG. True prophylactic treatment effect in a rat PTSD model on synaptic plasticity in ventral hippocampal and lateral amygdala along with potential molecular targets. Society for Neuroscience. October, 2019.
  • Edwards JG. Synaptic Plasticity: Modifying the brain from PTSD to addiction. Department of Neuroscience. September, 2019.
  • Edwards JG. CB1-Dependent LTD in ventral tegmental area GABA Neurons: A novel target for marijuana and cocaine. Endocannabinoid Research Group. August, 2019.
  • Edwards JG. chronic cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Gordan Research Conference- Cannabinoids. July, 2019.
  • Edwards JG. CB1-Dependent LTD in ventral tegmental area GABA Neurons: A novel target for marijuana . International Conference on Neurology and Brain Disorders. June, 2019.
  • Edwards JG, Neal E, Kimball S. Prophylatic treatment for PTSD-induced effect on plasticity. Life Science College Symposium. April, 2019.
  • Edwards JG, Johnson T, Winzenried E. PTSD treatment on hippocampal LTP. Mary Lou Fulton. April, 2019.
  • Edwards JG, Johnson T, Winzenried E, Kimball S, Moffat D, Melendez G. 2 posters. CURA Conference. March, 2019.
  • Edwards JG, Winzenried E, Neal E, Melendez G, Moffat D. 2 posters. Roseman Symposium. March, 2019.
  • Edwards JG. Ventral Tegmental Area GABA Neurons: A novel target for marijuana and cocaine reward/addiction. University of South Dakota. March, 2019.
  • Edwards JG, Kimball S, Neal E. Prophylatic Treatment for PTSD. Utah Academy of Sciences (UASAL). March, 2019.
  • Edwards JG, Neal E, Winzenried E, Robinson J, Moffat D, Melendez G. 3 oral presentations (2 students per presentation). Utah Confere nce for Undergraduate Research. February, 2019.
  • Edwards JG, Nufer T. BYU Grad Expo. 2018.
  • Edwards JG, Wizenried E, Jensen C. 1 Poster Presentation. Faculty for Undergraduate Neuroscience. November, 2018.
  • Edwards JG. Psychology Department. November, 2018.
  • Edwards JG, Ostlund I. 1 oral nanosymposium presentation. Society for Neuroscience. November, 2018.
  • Edwards JG, Wu B, Ostlund I, Pickard S, Jensen C, Miller R, Melendez G. 2 posters presented. Society for Neuroscience. 3 poster presentations at SfN (see CV for abstract titles/authors) . November, 2018.
  • Edwards JG, Wu B, Ostlund I, Winzenried E, Melendez G, Jensen C, Saito E. 3 Posters Presented. Society for Neuroscience Intermountain Branch. October, 2018.
  • Edwards JG. Summer Department Research Presentation. PDBio. June, 2018.
  • Edwards JG, Saito E. One Poster Presentation. Life Science College Symposium. April, 2018.
  • Edwards JG, Saito E, Pickard M, Mangum S. 3 poster presentations. Mary Lou Fulton Conference. April, 2018.
  • Edwards JG, Saito E, Melendez G, Jarman T, Jensen C, Picard S', Markam A. 4 Oral Presentations. Utah Conference on Ungraduate Research. February, 2018.
  • Edwards JG, Anderson B. 1 Poster Presentation. Faculty for Undergraduate Neuroscience. November, 2017.
  • Edwards JG, Nufer T, Ostlund I, Anderson B, Markham A. 3 posters presented. Society for Neuroscience. 3 poster presentations at SfN (see CV for abstract titles/authors) . November, 2017.
  • Edwards JG, Miller R, Ostlund I, Anderson B. 3 Posters Presented. Society for Neuroscience Intermountain Branch. October, 2017.
  • Edwards JG. Full Professor Seminar. PDBio Department Seminar. September, 2017.
  • Edwards JG. International Cannabinoid Research Society. July, 2017.
  • Edwards JG. Synaptic Plasticity: Addiction Mechanism of Marijuana. MMBio Research Seminar. May, 2017.
  • Edwards JG, Homan M, Call J, Gremillion M. 3 Oral Presentations. Utah Conference on Ungraduate Research. February, 2017.
  • Edwards JG. 1 Poster Presentation. Faculty for Undergraduate Neuroscience. November, 2016.
  • Edwards JG. 4 posters presented. Society for Neuroscience. 4 poster presentations at SfN. November, 2016.
  • Edwards JG. 2 Posters Presented. Society for Neuroscience Intermountain Branch. October, 2016.
  • Edwards JG. 2 Oral Presentations. Utah Conference on Ungraduate Research. February, 2016.
  • Edwards JG, Hammond T. 1 poster presented. Faculty for Undergraduate Neuroscience. October, 2015.
  • Edwards JG. 1 poster presented. Society for Neruoscience Intermountain Branch . October, 2015.
  • Edwards JG. 4 posters presented . Society for Neuroscience. October, 2015.
  • Edwards JG. Synaptic plasticity: From Addiction to Memory. BYU Psychology Department. March, 2015.
  • Edwards JG, Newton S, Welch J. 2 oral presentations. Utah Conference on Undergraduate Research. February, 2015.
  • Edwards JG, Newton S. 1 student presented 1 poster. Faculty for Undergraduate Neuroscience. November, 2014.
  • Edwards JG. Synaptic Plasticity- GABAergic cell role in memory and addiction. Uniformed Services University Health Sciences. November, 2014.
  • Edwards JG, Hurst K, Friend L, Newton S. 3 different poster presentations 1 undergraduate and 2 graduate . Intermountain Society for Neuroscience Branch Symposium. October, 2014.
  • Edwards JG, Newton S, Friend L, Hurst K, Haynie D. 4 different posters presented by 4 different authors. Society for Neuroscience. October, 2014.
  • Edwards JG. Synaptic Plasticity: From Learning and Memory to Addiction. PDBio/Neuroscience Seminar (BYU). March, 2014.
  • Mayo JL, Nichols BA, Olsen DS, Cordner RD, Hancock CR, Weber KS, Wilson E, Edwards JG, Barrow JR, Bridgewater LC. The nBMP2 mutant mouse shows defects in intracellular calcium transport-regulated pathways. Southwest Regional Meeting of the Society for Developmental Biology. March, 2014.
  • Edwards JG. The Putative Cannabinoid Receptor GPR55. Spring Brain Conference. March, 2014.
  • Edwards JG, Prince B, Nufer T, Trotter J. We had 2 different "oral" presentations from 3 different students . Utah Conference on Undergraduate Research. Four of my undergraduates had 'oral' research presentations from 4 different research projects . February, 2014.
  • Edwards JG, Hopkins Z. 1 student presented 1 poster. Faculty for Undergraduate Neuroscience. October, 2013.
  • Edwards JG, Hurst K, Hopkins Z. 2 different poster presentations 1 undergraduate and 1 graduate . Intermountain Society for Neuroscience Branch Symposium. October, 2013.
  • Edwards JG, Merrill C, Friend L, Hurst K, Hopkins Z. 4 different posters presented by 4 different authors. Society for Neuroscience. October, 2013.
  • Edwards JG. Synaptic Plasticity: From Learning and Memory to Addiction. LDSLSRS. July, 2013.
  • Edwards JG, Merrill c. BYU Graduate Expo. March, 2013.
  • Edwards JG, Marriott D, Schneider R, Bell S, Williamson R. We had 4 different "oral" presentations from 4 different students . Utah Conference on Undergraduate Research. Four of my undergraduates had 'oral' research presentations from 4 different research projects . February, 2013.
  • Merrill C, McNeil M, Pool BR, Nelson B, Sudweeks SN, Edwards JG. Identification of endocannabinoid biosynthetic enzyme mRNA in hippocampal pyramidal cells and CA1 stratum radiatum interneurons. Annual Meeting of the Society for Neuroscience. The hippocampus is required for short-term memory and contains both excitatory pyramidal cells and inhibitory interneurons Both cell types exhibit various forms of synaptic plasticity, the mechanism underlying learning and memory Recently, endocannabinoids (eCBs) have been identified to be involved in many types of plasticity including a novel long-term depression between CA3 pyramidal cells and CA1 stratum radiatum interneurons where the interneuron itself was suggested to produce the eCB involved However, the expression pattern of eCB biosynthetic enzymes within stratum radiatum interneurons has been unclear, and their capacity to produce eCBs debated Therefore, our goal was to describe the distribution of eCB biosynthetic enzymes within CA1 stratum radiatum interneurons and CA3/CA1 pyramidal cells using real-time quantitative PCR (RT-qPCR) We extracted RNA from single cells using patch electrodes and after reverse transcription, used probe based RT-qPCR to detect the presence of 12-lipoxygenase, N-acyl-phosphatidylethanolamine-specific phospholipase D, diacylglycerol lipase α, as well as type I metabotropic glutamate receptors, which are known to be involved in eCB production and plasticity Interneuron markers such as parvalbumin, calbindin, calretinin, and cholecystokinin were used to correlate eCB biosynthetic enzyme expression to interneuron subtype Spiking patterns recorded from interneurons, while varied, support categorization of interneuron subtypes based on these markers Results identified that eCB biosynthetic enzyme mRNA is expressed within interneurons and is indeed coexpressed with type I metabotropic glutamate receptors, suggesting that stratum radiatum interneurons could putatively produce eCBs necessary for synaptic plasticity This expression is also subtype-specific For example, mGluR5 was coexpressed with diacylglycerol lipase α and N-acylphosphatidylethanolamine-specific phospholipase D, but not 12-lipoxygenase; while mGluR1 was coexpressed with all tested eCB biosynthetic enzymes, mainly in cholecystokinin-calbindin cells In addition, we identified that CA3 and CA1 pyramidal cells express eCB biosynthetic enzyme mRNA Finally, quantitative levels of expression illustrate very similar amounts of type I metabotropic glutamate receptors in interneurons versus pyramidal cells, with some differences in eCB biosynthetic enzyme mRNA between them Collectively, our data provide the first RT-qPCR evidence for putative eCB production in interneurons, suggesting their potential ability to regulate eCB-mediated processes such as synaptic plasticity. October, 2012.
  • Williamson R, Edwards JG. Endocannabinoid biosynthesizing enzyme expression in hippocampal stratum oriens. National Conference of Undergraduate Research. February, 2012.
  • Wallmann A, Edwards JG. TRPV1 agonist plasticity of hippocampal LTP. National Conference of Undergraduate Research. February, 2012.
  • TAYLOR D, BURMAN PN, WILCOX RS, MERRILL CB, RINGER K, Sudweeks SN, Edwards JG, ARIAS HR, WU J, Steffensen SC. Acute and chronic effects of nicotine on GABA neurons in the ventral tegmental area. Annual Meeting of the Society for Neuroscience. Nicotine (NIC) abuse involves activation of midbrain dopamine (DA) neurons and NIC addiction involves neuroadaptive changes in the mesolimbic DA reward system GABA neurons in the midbrain ventral tegmental area (VTA) express α4β2-containing nicotinic acetylcholine receptors (nAChRs), whose activation increases GABAergic input to DA neurons However, NIC activation of α4β2 nAChRs induces rapid desensitization Thus, the initial inhibitory effect on DA neurons is decreased after chronic NIC treatment (as in the case of smokers) We evaluated the effects of acute and chronic NIC on GAD-67 positive neurons in the VTA of GAD GFP mice using in vivo and in vitro electrophysiological methods In in vivo studies in naïve mice, IV NIC (07 mg/kg) markedly increased VTA GABA neuron firing rate with tachyphylaxis to repeated administration Microelectrophoretic application of NIC, or the α7 agonist JN403, also markedly increased VTA GABA neuron firing rate; however, tachyphylaxis did not accrue to repeated, periodic in situ administrations Nicotine and JN403 activation of VTA GABA neurons was blocked by IP administration of the α7 antagonist methyllycaconitine (1 mg/kg), but not by the unspecific noncompetitive antagonist mecamylamine (1 mg/kg) Chronic NIC injections (07 mg/kg/day for 2 weeks) did not significantly alter baseline GABA neuron firing rate, but did decrease their sensitivity to NIC In in vitro studies in naïve mice, NIC decreased GABA inhibition to GABA neurons (ie, sIPSCs), while chronic NIC injections increased sIPSCs Finally, while expression of α4β2 nAChRs in GABA neurons was unaffected, there was de novo expression of α6 containing receptors in GABA neurons in NIC- vs saline-treated mice Taken together, these findings indicate that NIC markedly excites VTA GABA neurons However, systemic NIC effects on GABA neurons are complex, and likely due to a combination of direct and indirect effects on GABA neurons and afferent inputs Acute tachyphylaxis accrues to repeated systemic, but not local applications of NIC, suggesting that limited local NIC does not desensitize nAChRs The pharmacological data indicates that local activation is likely mediated through α7 nAChRs on GLU terminals to VTA GABA neurons Chronic exposure to NIC results in reduced sensitivity to NIC and de novo α6 expression in one population of VTA GABA neurons, which may explain why chronic NIC results in enhanced GABA inhibition of DA neurons. November, 2011.
  • Edwards JG, Jensen T. Calcineurin is required for TRPV1-mediated LTD in the hippocampus. Society for Neuroscience. November, 2011.
  • Merrill C, Edwards JG. Expression of endocannabinoid biosynthesizing enzymes in hippocampal CA1 neuron. Society for Neuroscience. November, 2011.
  • Edwards JG, Williamson R. Expression of endocannabinoid enzymes in hippocampal neurons. Faculty for Undergraduate Neuroscience. October, 2011.
  • Wallmann A, Edwards JG. TRPV1 Modulation of Hippocampal Synaptic Plasticity. Intermountain Chapter Society for Neuroscience. October, 2011.
  • Taylor D, Edwards JG, Steffensen S. Acute and chronic effects of nicotine on GABA neurons in the ventral tegmental area. Society for Neuroscience. October, 2011.
  • Edwards JG, Wallmann A. Transient receptor potential vanilloid 1 agonists modulate hippocampal CA1 LTP via the GABAergic system. Society for Neuroscience. October, 2011.
  • Chamberlin P, Edwards JG. Life Science Poster Session. Oral Presenation only. August, 2011.
  • Williamson R, Edwards JG. Endocannabinoid mRNA expression in hippocampus. Ira Fulton Conference. Oral Presentation only. April, 2011.
  • Wallmann A, Edwards JG. TRPV1 involvement in hippocampal plasticity. Ira Fulton Conference. Oral Presenation only. April, 2011.
  • Muir C, Edwards JG. TRPV1 mediated metaplasticity of hippocampal CA1 long-term potentiation and long-term depression. Utah Conference on Undergraduate Research. March, 2011.
  • Jensen T, Edwards JG. Calcineurin is required for hippocampal interneuron LTD. Intermountain Graduate Research Symposium. Oral Presentation. February, 2011.
  • Merrill C, Edwards JG. Endocannabinoid expression and invovlement in hippocampal function. Intermountain Graduate Research Symposium. Oral Presentation. February, 2011.
  • Steffensen S, Bradley K, Edwards JG. Role of connexin-36 gap junctions in alcohol intoxication and reward. Alcoholism: Clinical experimental research. 2010.
  • Cordner R, Edwards JG, Bridgewater L. Mice bearing a targeted mutation of nBmp2 display decreased memory capabilities . American Society for Biochemistry and Molecular Biology . 2010.
  • Hansen DM, Edwards JG, Steffensen S. The role of connexin-36 gap junctions between GABA neurons in the ventral tegmental area in alcohol intoxication and reward . Annual Meeting of the Society for Neuroscience. 2010.
  • Steffensen SC, TAYLOR DH, BURMAN PN, WILCOX RS, RINGER K, MERRILL CB, Sudweeks SN, Edwards JG, ARIAS HR. Acute and chronic effects of nicotine on GABA neurons in the ventral tegmental area. Annual Meeting of the Society for Neuroscience. November, 2010.
  • Merrill C, Edwards JG. Identification of endocannabinoid components within hippocampal CA1 interneuron subtypes. Annual Meeting of the Society for Neuroscience. November, 2010.
  • Jensen T, Edwards JG. Transient receptor potential vanilloid 1 modulation of hippocampal synaptic plasticity. Annual Meeting of the Society for Neuroscience. November, 2010.
  • McNeil M, Edwards JG. Endocannabinoid component indentification within hippocampal CA1 interneuron subtypes. Faculty for Undergraduates in Neuroscience. November, 2010.
  • Edwards JG. Hippocampal interneuron expression of endocannabinoid signaling components . Society for Neuroscience Intermountain Chapter- Snowbird. October, 2010.
  • Wilcox J, Edwards JG, Steffensen S. Role of connexin-36 gap junctions in alcohol intoxication and reward. Society for Neuroscience Intermountain Chapter- Snowbird. October, 2010.
  • Jensen T, Edwards JG. TRPV1 mediated metaplasticity of Hippocampal CA1 LTP and LTD . Society for Neuroscience Intermountain Chapter- Snowbird. October, 2010.
  • Edwards JG, McNeil M. Life Science College Poster Presentations. August, 2010.
  • Edwards JG, Blickenstaff J. Life Science College Poster Presentations. August, 2010.
  • Merrill C, Edwards JG. Endocannabinoid component expression in the hippocampus. Intermountain Gradaute Research Symposium. Oral Presentation. June, 2010.
  • Jensen T, Edwards JG. TRPV1 involvment in hippocampal synaptic plasticity. Intermountain Gradaute Research Symposium. Oral Presentation. June, 2010.
  • Cordner RD, Ventura JS, Blickenstaff JW, Walther CK, Mayo JL, Felin JE, Andreasen B, Wallace NB, Cappechi MR, Edwards JG, et alMice bearing a targeted mutation of nBmp2 display decreased memory capabilities. Experimenal Biology 2010. April, 2010.
  • Edwards JG. Learning and Memory Mechanisms in the Hippocampus: AMPA Receptor Movement and Insertion. Biology Department Seminar. 2009.
  • Bennion D, Jensen T, Walther C, Mors M, Edwards JG. TRPV1 Modulation of LTP. Faculty for Undergradaute Education Conference. 2009.
  • Edwards JG. Learning and Memory: Student Oriented Issues. High school science teachers. 2009.
  • Edwards JG. Learning and Memory Mechanisms in the Hippocampus. Neuroscience Seminar. 2009.
  • Merrill C, Nelson B, Martin A, Edwards JG. Hippocampal interneuron expression of endocannabinoid signaling components. Society for Neuroscience International Conference. 2009.
  • Bennion D, Jensen T, Walther C, Mors M, Edwards JG. TRPV1 modulation of plasticity in the hippocampus. Society for Neuroscience International Conference. 2009.
  • Bennion D, Jensen T, Couch J, Castle M, Daniel S, Nelson B, Edwards JG. TRPV1 Hippomcampal Modulation. Utah Conference on Undergradaute Research. 2009.
  • JENSEN T, BENNION D, COUCH J, CASTLE M, DANIEL S, Edwards JG. TRPV1 Modulation. International group of undergraduates and their mentors. wwwfunfacultyorg/. 2008.
  • JENSEN T, BENNION D, COUCH J, CASTLE M, DANIEL S, Edwards JG. TRPV1 Modulation of the Hippocampus. International audience. wwwabstractsonlinecom/plan/ViewAbstractaspx?sKey=2600dacf-68bc-42cb-bb42-fe0faccb8eb2&cKey=50effd66-c625-4105-8e84-708092bad12e. November, 2008.