Antimicrobial peptides (AMPs) are small, amino acid-based molecules with antimicrobial properties. Our research focuses on engineering E. coli to produce novel cyclic AMPs for potential clinical application as antibiotics.
Chromoproteins
Chromoproteins are proteins that naturally fold to reflect visible light, producing vibrant colors such as pink, yellow, blue, and purple. Our research focuses on engineering the amino acid sequences of these proteins to explore the potential for generating new colors and discovering novel properties.
In Vivo DNA Assembly Technology
In Vivo DNA Assembly technology uses natural cell machinery to join DNA fragments inside living organisms. Our research focuses on engineering E. coli genome by modifying its chromosome, either by removing or adding functions to optimize the DNA Assembly process.
Regulation of Heavy Metal Tolerance in Bacteria
Understanding Salt Tolerance in Soil Bacteria and Host Plants
Salt resistance in Sinorhizobium bacteria is a key trait that allows these organisms to survive in high-salinity environments. Our research uses a transposon-based approach with plasmids to knock out individual genes, aiming to identify those that are critical for salt tolerance and to deepen our understanding of bacterial stress responses.
