Publications

O'Neill KL, Weagel EG, Meng W, Townsend M, Velazquez EJ, Brog RA, Boyer MW, Weber KS, Robison RA. 2018. Biomarker analysis and clinical relevance of TK1 on the cell membrane of Burkitt’s lymphoma and acute lymphoblastic leukemia. Oncotargets and Therapy. doi:https://dx.doi.org/10.2147%2FOTT.S141239

Weagel EG, Meng W, Townsend MH, Velazquez-Espinoza E, Brog RA, Weber KS, Robison RA, O’Neill KL. 2017. Biomarker analysis and clinical relevance of thymidine kinase 1 on the cell membrane of Burkitt’s lymphoma and acute lymphoblastic leukemia. OncoTargets and Therapy. 10:4355-4367.

Townsend M, Felsted AM, Piccolo SR, Robison RA, O'Neill KL. 2017. Metastatic colon adenocarcinoma has a significantly elevated expression of IL-10 compared to primary colon adenocarcinoma tumors. Cancer Biology & Therapy.

Townsend MH, Anderson MD, Weagel EG, Velazquez EJ, Weber KS, Robison RA, O'Neill KL. 2017. Non-Small Cell Lung Cancer Cell lines A549 and NCI-H460 Express HPRT on the Plasma Membrane. Oncotargets and Therapy. 2017. doi:https://doi.org/10.2147/OTT.S128416

Townsend MH, Peck CJ, Meng W, Heaton MJ, Robison RA, O'Neill KL. 2017. Evaluation of Various Glyphosate Concentrations on DNA Damage in Human Raji Cells and its Impact on Cytotoxicity. Regulatory Toxicology and Pharmacology. 85:79-85.

Steck R, Hill S, Weigel E, Weber KS, Robison RA, O'Neill KL. 2015. Pharmacologic immunosuppression of mononuclear phagocyte phagocytosis by caffeine.. Pharmacology Research & Perspectives. 3(6). doi:10.1002/prp2.180

Weagel E, Smith C, Liu P, Robison RA, O'Neill KL. 2015. Macrophage polarization and its role in cancer. J. Clin. Cell Immunol. 6(4):1-8.

Shrestha G, StClair LL, O'Neill KL. 2014. The immunostimulating role of lichen polysaccahrides: A Review. Phytotherapy Research. doi:10.1002/ptr.5251

Shrestha G, El-Naggar AM, StClair LL, O'Neill KL. 2014. Anticancer Activities of Selected Species of North American Lichen Extracts. Phytotherapy Research. doi:10.1002/ptr.5233

Clifford AB, Elnaggar AM, Robison RA, O'Neill KL. 2013. Investigating the role of macrophages in tumor formation using a MaFIA mouse model. Oncology Reports. 30(2):890-896. doi:10.3892/or.2013.2508

Lowe C, March JK, Bunnell AJ, O'Neill KL, Robison RA. 2013. PCR-based methodologies used to detect and differentiate the Burkholderia pseudomallei complex: B. pseudomallei, B. mallei, and B. thailandensis. Current Issues in Molecular Biology. 16:23-54.

Robison RA, O'Neill KL. 2013. Thymidine kinase 1: a universal marker for cancer. Cancer and Clinical Oncology. 2(1):159-167.

Robison RA, March JK, Cohen MN, Lindsey JM, Millar DA, Lowe C, Bunnell AJ, Schaalje GB, O'Neill KL. 2012. The differential susceptibility of spores from virulent and attenuated Bacillus anthracis strains to aldehyde- and hypochlorite-based disinfectants. MicrobiologyOpen. 1-8.

Robison RA, Gunnell MK, Lovelace CD, Satterfield BA, Moore EA, O'Neill KL. 2012. A multiplex real-time PCR assay for the detection and differentiation of Francisella tularensis subspecies. Journal of Medical Microbiology. 61:1525-1531.

Gupta-Elera G, Garrett A, Martinez A, Kraus R, Robison RA, O'Neill KL. 2012. A Comparison of Antioxidant Properties in Organic and Conventional Blueberries. Journal of Food Research. 1(3):1-7.

Alegre M, Robison RA, O'Neill KL. 2012. Thymidine kinase 1 upregulation is an early event in breast tumor formation. Journal of Oncology. 2012:5.

Alegre MM, Robison RA, O'Neill KL. 2012. Thymidine kinase 1upregulation is an early event in breast tumor formation. Journal of Oncology. 1-5. doi:10.1155/2012/575647

Gupta G, Garrett A, Robison RA, O'Neill KL. 2012. The role of oxidative stress in prostate cancer -a review. European Journal of Cancer Prevention. 21(2):155-162.

Satterfield BA, Stewart AF, Lew CS, Pickett DO, Cohen M, Moore EA, Luedtke PF, O'Neill KL, Robison RA. 2010. A quadraplexed real-time PCR assay for rapid detection and differentiation of the Clostridium botulinum toxin genes A, B, E and F. Journal of Medical Microbiology. 59(1):55-64.

Velazquez EJ, Brindley TD, Shrestha G, Skabelund RA, Lee CM, Ewell ZD, Bitter EE, Townsend MH, Bennion KB, Ong KL, et al. Generation and characterization of a panel of monoclonal antibodies against the tumor biomarker thymidine kinase 1 for research, clinical and therapeutic applications. American Association for Cancer Research Annual Meeting. Atlanta, GA. 2019 .
Townsend MH, Ewell ZD, Tellez Freitas CM, Larsen DJ, Lawerence EL, Bennion KB, Piccolo SR, Weber KS, Robison RA, O'Neill KL. HPRT Overexpression May Contribute to the Immunosuppressive Tumor Microenvironment. Annual Meeting of the American Association for Cancer Research. Atlanta Georgia. 2019 .

Townsend MH, Bennion K, Weagel EG, Whitley K, Velazquez E, Weber KS, O'Neill KL. Mechanistically Minded: A study of the surface co-localization of salvage pathway enzymes. National Symposium for Undergraduate Research. Memphis, Tennessee. 2018 .

Townsend MH, Felsted AM, Ence Z, Piccolo SR, Robison RA, ONeill K. HPRT Upregulation in cancer and its potential use as a diagnostic and prognostic biomarker. BYU Biomedical Symposium. BYU. 2018 .

Townsend MH, Cox TP, Felsted AM, Lattin JE, Ence Z, Robison RA, Piccolo SR, ONeill K. HPRT’s surface expression and biochemical connection tp53 in prostate cancer. BYU Biomedical Symposium. BYU. 2018 .

O'Neill KL. Understanding Cancer. 109th annual meeting of the AACR. Chicago, Illinois. 2018 .

Townsend MH, Ence ZE, Cox TP, Lattin JE, Burrup W, Piccolo SR, Robison RA, O'Neill KL. Evaluation of the upregulation and surface presentation of HPRT as an immunotherapy target for the treatment of B cell malignancies. Cancer and Immunotherapy Symposium. Chicago, Illinois. 2018 .

Townsend MH, Clay T, Felsted AM, Burrup W, Weagel EG, Velazquez EJ, Weber KS, Robison RA, O'Neill KL. Evaluating surface expression of the nucleotide salvage pathway enzyme HPRT on colorectal cancer cells. Undergraduate Student Caucus and Poster competition in Chicago, Illinois. Chicago, Illinois. 2018 .

ONeill K, Townsend MH. Upregulation of housekeeping HPRT1 gene in malignancies hinders subsequent use as an endogenous control. President’s Leadership Council. BYU. 2018 .

Townsend MH, Felsted AM, Cox TP, Ence ZE, Lattin JE, Boyer MK, Piccolo SR, Robison RA, O'Neill KL. Surface Localization of HPRT and it’s implication as an immunotherapy target for B cell malignancies. Simmons Center for Cancer Research Annual Donor Appreciation Dinner. BYU. 2018 .

Townsend MH, Felsted A, Weagel EG, Velazquez EJ, Robison RA, ONeill K. Diagnostic potential of salvage pathway enzymes for the treatment of lung cancer. Brigham Young University Undergraduate Annual Poster Competition. Provo, Utah. 2017 .

Peck CJ, Townsend MH, O'Neill KL. Resveratrol and pterostibene selectively chemosensitize Burkitt’s lymphoma cells to 5-Fluorouracil. AACR 108th annual meeting. Washington DC. 2017 .

Townsend MH, Anderson MD, Weagel EG, Velazquez EJ, Scott Weber K, Robison RA, O'Neill KL. Unusual HGPRT expression on the surface of the colorectal cancer cell lines HT29 and SW620. AACR 108th annual meeting. Washington DC. 2017 .

Weagel EG, Townsend MH, Anderson MD, Velazquez EJ, Weber KS, Robison RA, O’Neill KL. Unusual expression of HPRT on the surface of the colorectal cancer cell lines HT29 and SW620. American Association for Cancer Research. Washington D.C. 2017 .

Townsend MH, Felsted AM, Clarke J, Robison RA, O'Neill KL. HPRT expression in breast carcinoma and its use as a diagnostic biomarker. American Association for Cancer Research Undergraduate Student Caucus and Poster Competition. Washington DC. 2017 .

Townsend MH, Burrup W, Weagel E, Felsted A, Anderson MD, Velazquez EJ, Scott Weber K, Robison RA, O'Neill KL. HPRT: Could it be used as a biomarker for future immunotherapies?”. American Association for Cancer Research Undergraduate Student Caucus and Poster Competition. Washington DC. 2017 .

Peck CJ, Townsend MH, O'Neill KL. Resveratrol and pterostilbene selectively chemosensitize Burkitt’s lymphoma cells to 5-Flourouracil. American Association for Cancer Research Undergraduate Student Caucus and Poster Competition. Washington DC. 2017 .

Townsend M, Brindley TD, Felsted A, Weagel E, Velazquez EJ, Robison RA, O'Neill KL. Evaluation of Hypoxanthine Guanine Phosphoribosyltransferase expression in prostate cancer and its implication on therapy. American Society of Microbiologists Intermountain Branch. Ogden Utah. 2017 .

Townsend M, Olsen E, Felsted A, Robison RA, O'Neill KL. Metastatic colorectal cancer tumors express higher levels of IL-10 than primary colorectal tumors. American Society of Microbiologists Intermountain Branch. Ogden Utah. 2017 .

Townsend M, Olsen E, Felsted A, Robison RA, O'Neill KL. Metastatic colorectal cancer tumors express higher levels of IL-10 than primary colorectal tumors. American Society of Microbiologists Intermountain Branch. Ogden Utah. 2017 .

Townsend MH, Lattin JE, Anderson MD, Felsted A, Weagel E, Velasquez E, Robison R, O'Neill KL. Salvage pathway enzyme HPRT as a molecular marker for Burkitt’s Lymphoma. Annual meeting of the American Association for Cancer Research. Washington DC. 2017 .

Velazquez E, Ewell Z, Lattin J, Vaden K, Townsend MH, Weber KS, Robison RA, O'Neill KL. A pre-clinical study of chimeric antigen receptor (CAR) T cells targeting Thymidine Kinase 1 (TK1) in lung cancer cell lines. Presented at the American Society of Microbiologists Intermountain Branch. Ogden Utah. 2017 .

StClair LL, Gajendra S, D. LS, O'Neill KL. Can we cure cancer with lichens?. American Bryological and Lichenological Society. New Orleans, Louisiana. 2013 .

Memmott T, Weagel E, Livingstone J, Liu P, Elnaggar A, Robison RA, O'Neill KL. Investigating macrophage induction of metastasis: a precursor to identify therapeutic targets. American Society of Gene and Cell Therapy. Salt Lake City. 2013 .

Shrestha, G, Elnaggar A, Boswell M, Derenthal S, Weagel E, StClair LL, Robison RA, O'Neill KL. Cytototoxicity and mode of action of two lichen extracts, Tuckermannopsis ciliaris and Xanthoparmelia chlorochroa against Burkitt’s Lymphoma (Raji) cell and Human colon cancer cell line (HT-29)’. 8th Annual Undergraduate Student Caucus and Poster Competition. Washington DC. 2013 .

Steck R, Wells M, Elnaggar A, O'Neill KL. Phagocytic regulation through exogenous caffeine exposure in whole-blood macrophages. 8th Annual Undergraduate Student Caucus and Poster Competition. Washington DC. 2013 .

Helsing AV, Lynch P, Xiao M, Ramsden M, Alegre F, Weagel E, Elnaggar A, McCoy J, Robison RA, O'Neill KL. The Potential of Resveratrol and Nagami Kumquat extracts in facilitating DNA repair in Raji cells’. 8th Annual Undergraduate Student Caucus and Poster Competition. Washington DC. 2013 .

Shrestha, G, Elnaggar A, Boswell M, Dereenthal S, Weagel E, StClair LL, Robison RA, O'Neill KL. Cytototoxicity and mode of action of two lichen extracts, Tuckermannopsis ciliaris and Xanthoparmelia chlorochroa against Burkitt’s Lymphoma (Raji) cell and Human colon cancer cell line (HT-29)’. Annual Meeting. Washington DC. 2013 .

Weagel E, Martinez A, Elnaggar A, Ellis S, Liu P, Robison RA, O'Neill KL. Differences in cellular antioxidant activity in Burkitt’s lymphoma and normal human lymphocytes’. Annual Meeting. Washington DC. 2013 .

Xiao M, Elnaggar A, Helsing A, Lynch P, Alegre M, Robison RA, O'Neill KL. Mutagenic effects of inorganic particulate matter on Raji and HepG2 cell lines exposed to ultraviolet radiation’. Annual Meeting. Washington DC. 2013 .

Steck R, Wells M, Liu P, ELnaggar A, O'Neill KL. Phagocytic regulation through exogenous caffeine exposure in whole-blood macrophages. Annual Meeting. Washington DC. 2013 .

Hesling A, Elnaggar A, Lynch P, Xiao M, Ramsden M, Alegre F, Weagel E, McCoy J, Robison RA, O'Neill KL. The Potential of Resveratrol and Nagami Kumquat extracts in facilitating DNA repair in Raji cells’. Annual Meeting. Washington DC. 2013 .

O'Neill KL, Livingstone J, Lee E, Barlow S, ELnaggar A, Weagel E, Liu P, Robison RA. Macrophages may be polarized by apoptotic and necrotic cancer cells. intermountain Branch meeting of the American Society for Microbiology. Idaho State University, Pocatello, Idaho,. 2013 .

O'Neill KL, Elnaggar A, Clement A, Robison RA. A Tumor Microenvironment Rich in Macrophages could be Aiding Metastasis’. Molecular and Cellular Biology. Dublin, Ireland. 2012 .

O'Neill KL, Kraus R, Martinez A, Measom K, Gill M, Gupta-Elera G, Garrett A, Robison RA. Blueberries: Conventional Cancer Prevention. Annual Meeting of the American Association for Cancer Research. Chicago. 2012 .

O'Neill KL, Elnaggar A, Chavez A, Peterson E, Kuttab R, Robison RA. S2AMN: A potential non- toxic anti-cancer therapy. Annual Meeting of the American Association for Cancer Research. Chicago. 2012 .

O'Neill KL, Alegre M, Germann B, Leavitt M, Eggett D, Killpack N, Burton S, Orton A, Leavitt C. Setting the Clock: Tumor TK1 is a Prognostic Marker for Disease Recurrence. Annual Meeting of the American Association for Cancer Research. Chicago. 2012 .

O'Neill KL, Measom K, Martinez A, Sharp E, Michaelis T. ‘How ‘Bout them Apples?. Annual Meeting of the American Association for Cancer Research. Chicago. 2012 .

O'Neill KL, McCoy J, Grooms A, Emerson J, Kraus R, Martinez A, Elnaggar A. ‘Fortunella margarita: The little gold gem of the citrus family. Undergraduate Caucus of the American Association for Cancer Research. Chicago. 2012 .

O'Neill KL, Measom K, Martinez A, Sharp E, Michaelis TC. ‘How ‘Bout them Apples?. Undergraduate Caucus of the American Association for Cancer Research. Chicago. 2012 .

Jensen NR, O'Neill KL, Robison RA. CRISPR loci and bacteriophage: a mutually exclusive relationship in pathogenic bacteria. Annual Meeting of the Intermountain Branch of the American Society for Microbiology. Ogden, UT. 2011 .

Meyers JM, Ryndock E, Conway MJ, Meyers CM, O'Neill KL, Robison RA. The susceptibility of HPV16 native and quasivirus particles to clinically relevant disinfectants. 26th International Papillomavirus Conference. Montreal, Qc, Canada. 2010 .

Bills TM, Shepherd QC, Blam AJ, Moore EA, Gardner JS, Schaalje GB, O'Neill KL, Robison RA. Improved recovery of spores from coated carriers used in the AOAC Sporicidal Activity of Disinfectants (Method II) spore enumeration method, by addition of a surfactant to the rinse solution. General Meeting of the American Society for Microbiology. San Diego, CA. 2010 .

Meyers JM, Ryndock E, Conway MJ, O'Neill KL, Meyers CM, Robison RA. Susceptibility of native and synthetic HPV16 virions to clinical disinfection. General Meeting of the American Society for Microbiology. San Diego, CA. 2010 .

Bills TM, Shepherd QC, Blam AJ, Moore EA, Gardner JS, Schaalje GB, O'Neill KL, Robison RA. Improved recovery of spores from coated carriers used in the AOAC Sporicidal Activity of Disinfectants (Method II) spore enumeration method, by addition of a surfactant to the rinse solution. Intermountain Branch of the American Society for Microbiology Annual Meeting. Provo, UT. 2010 .

Gunnell MK, Carter CD, Jonas WS, Satterfield BA, Moore EA, O'Neill KL, Robison RA. A multiplex real-time PCR assay for the detection and differentiation of Francisella tularensis subspecies. 3rd Annual Biothreat Agent Workshop. Charlotte, NC. 2010 .