Publications

Atypical chemokine receptor ACKR2-V41A has decreased CCL2 binding, scavenging, and activation, sustaining inflammation and increasing Alzheimer's disease risk (opens in a new tab)

Gonzalez Murcia JD, Weinert A, Freitas CMT, Arens DK, Ferrel M, Grose JH, Wilson E, Kauwe JSK^*, Weber KS^* (2020) Scientific Reports doi.org/10.1038/s41598-020-64755-1

Novel monoclonal antibodies against thymidine kinase 1 and their potential use for immunotargeting of lung, breast, and colon cancer cells (opens in a new tab)

Velazquez EJ, Brindley TD, Shrestha G, Bitter EE, Cress JD, Townsend MH, Berges BK, Robison RA, Weber KS and O’Neill KL (2020) Cancer Cell International. doi: 10.1186/s12935-020-01198-8

Hypoxanthine Guanine Phosphoribosyltansferase expression is negatively correlated with immune activity through its regulation of purine synthesis (opens in a new tab)

Townsend MH, Freitas CMT, Larsen D, Piccolo SR, Weber KS, Robison RA, and O’Neill KL (2020) Immunobiology. doi: 10.1016/j.imbio.2020.151931

Obesity and CD8 T cell Metabolism: Implications for anti-tumor immunity and cancer immunotherapy outcomes (opens in a new tab)

Turbitt WJ, Weber KS, and Norian LA (2020) Immunological Reviews. doi: 10.1111/imr.12849

Genomics Education in the Era of Personal Genomics: Academic, Professional, and Public Considerations (opens in a new tab)

Tueller JA, Whitley KV, and Weber KS. (2020) International Journal of Molecular Sciences. doi: 10.3390/ijms21030768

A Full Semester Flow Cytometry Course Improves Graduate and Undergraduate Student Confidence and Interest (opens in a new tab)

Tueller JA, Whitley KV, and Weber KS. (2019) Biochemistry and Molecular Biology Education. doi: 10.1002/bmb.21318

Associations between evaporative cooling and dust mite allergens, endotoxins, and  (opens in a new tab)β (opens in a new tab)-(1-3)-D-glucans in house dust: (opens in a new tab)

A study of low income homes. (opens in a new tab)

Johnston JD^*, Cowger AE^*, Graul RJ, Nash R, Tueller JA, Hendrickson NR, Robinson DR, Beard J, Weber KS. (2019) Indoor Air. doi: 10.1111/ina.12600

The nuclear variant of bone morphogenic protein 2 (nBMP2) is expressed in macrophages and alters calcium response (opens in a new tab)

   Freitas CMT, Burrell HR, Valdoz JC, Hamblin GJ, Raymond CM, Cox TD, Johnson DK, Anderson JL, Weber KS, and Bridgewater LC (2019) Scientific Reports.  doi.org/10.1038/s41598-018-37329-5

Common microbial metabolites of dietary flavonoids exert potent anti-diabetes activities in β-cell and skeletal muscle cell models (opens in a new tab)

   Bitner BF, Ray JD, Kener KB, Herring JA, Tueller JA, Johnson DK, Freitas CMT, Weber KS, Allen M, Thompson A, Fausnacht D, McMillian RP, Hulver MW Brown DA, Tessem JS, and Neilson AP (2018) Journal of Nutritional Biochemistry. doi: 10.1016/j.jnutbio.2018.09.004

  (opens in a new tab)Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies (opens in a new tab)

  Weagel EG, Burrup W, Kovtun R, Velazquez EJ, Felsted AM, Townsend MH, Ence ZE, Suh E, Piccolo SR, Weber KS, Robison RA, and O’Neill KL (2018) Cancer Cell International. 18(135); doi: 10.1186/s12935-018-0633-9

T cell calcium signaling regulation by the CD5 co-receptor (opens in a new tab)

  Freitas CMT, Johnson DK, and Weber KS. (2018) International Journal of Molecular Science. 19(5), 1295; doi: 10.3390/ijms19051295

Personal microbiome analysis increases engagement & interest in Immunology, Genomics, & Molecular Biology undergrad courses (opens in a new tab)

   Weber KS, Bridgewater LC, Jensen JL, Breakwell D, Nielsen B, and Johnson SM. (2018) PLoS ONE. 13(4); e0193696. https//doi.org/10.1371/journal.pone.0193696

Using Backward Design in Education Research (opens in a new tab)

Jensen J, Bailey E, Kummer T, and Weber KS. (2017) Journal of Microbiology and Biological Education. December 201718(3): DOI: https://doi.org/10.1128/jmbe.v18i3.1367

Biomarker analysis and clinical relevance of TK1 on the cell membrane of Burkitt's lymphoma and acute lymphoblastic leukemia (opens in a new tab)

  Weagel EG, Meng W, Townsend MH, Velazquez EJ, Brog RA, Boyer MW, Weber KS, Robison RA, and O'Neill KL (2017) OncoTargets and Therapy. September 6, 2017. 10:4355-4367

Naive T helper cell with high CD5 levels has improved calcium mobilization (opens in a new tab)

  Freitas CMT, Hamblin GJ, Raymond CM, and Weber KS (2017) PLoS ONE. 12(5): e0178799

Method to Increase Undergraduate Laboratory Student Confidence in Performing Independent Research (opens in a new tab)

Kempton CE, Weber KS, and Johnson SM (2017) Journal of Microbiology & Biology Education. April 21, 2017 18(1) DOI: https://doi.org/10.1128/jmbe.v18i1.1230

Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine (opens in a new tab)

Townsend MH, Anderson MD, Weagel EG, Velazquez EJ, Weber KS, Robison RA, and O'Neill KL (2017) OncoTargets and Therapy. Mar 30, 2017. 10:1921-1932 doi: 10.2147/OTT.S128416

Evaporative Cooler Use Influences Temporal Indoor Relative Humidity but Not Dust Mite Allergen Levels in Homes in a Semi-Arid Climate​ (opens in a new tab)

​Johnston JD, Tuttle SC, Nelson MC, Bradshaw RK, Hoybjerg TG, Johnson JB, Kruman BA, Orton TS, Cook RB, Eggett DL, Weber KS (2016) PLoS ONE. 11(1): e0147105. doi:10.1371/journal.pone.0147105

Pharmacologic immunosuppression of mononuclear phagocyte phagocytosis by caffeine (opens in a new tab)

Steck R, Hill S, Weigel E, Weber KS, Robison R, O’Neill K. (2015) Pharmacology Research & Perspectives. 3(6), e00180, doi: 10.1002/prp2.180

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model (opens in a new tab)

Olsen DS, Goar WA, Nichols BA, Bailey KT, Christensen SL, Merriam KR, Reynolds PR, Wilson E, Weber KS, and Bridgewater LC​. (2015) BioMed Research International. Volume 2015, Article ID 975789

Anticipation of Personal Genomics Data Enhances Interest and Learning Environment in Genomics and Molecular Biology Undergraduate Classrooms (opens in a new tab)

Weber KS, Jensen JL, and Johnson SM. (2015) PLoS ONE. 10(8)e0133486

Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC (opens in a new tab)

Persuad SP, Parker CR, Lo WL, Weber KS, and Allen PM. (2014) Nature Immunology. 15(3):266-274. 

Article summary/News and Views (opens in a new tab) feature (opens in a new tab)

Subtle changes in TCRa CDR1 profoundly increases th​e sensitivity of CD4 T cells (opens in a new tab)

Lynch JN, Donermeyer DL, Weber KS, Kranz DM, and Allen PM. (2013) Molecular Immunology. 53(3):283-294.

Dynamics of CD4+ T cell responses against Listeria monocytogenes (opens in a new tab)

Graw F, Weber KS, Allen PM and Perelson AS. (2012) Journal of Immunology. 189(11):5250-5256.

Distinct CD4 (opens in a new tab)⁺ (opens in a new tab) helper T cells involved in primary and secondary responses to infection (opens in a new tab)

Weber KS, Li QJ, Persaud SP, Campbell JD, Davis MD, and Allen PM. (2012)  Proceedings of the National Academy of Sciences. U S A . 109(24):9511-9516  Faculty of 1000 recommended.

Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization (opens in a new tab)

Weber KS, Hildner K, Murphy KM, and Allen PM. (2010) Journal of Immunology. 185(5):2836-46

High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics (opens in a new tab)

Persaud SP, Donermeyer DL, Weber KS, Kranz DM, and Allen PM. (2010)  Molecular Immunology. 47(9):1793-801.

Protein kinase C-theta is required for efficient positive selection (opens in a new tab)

Morley, SC, Weber KS, Kao H, and Allen PM. (2008) Journal of Immunology. 181(7):4696-4708.

Th17 cells exhibit a distinct calcium profile from Th1 and Th2 cells and have Th1-like motility and NFAT nuclear localization (opens in a new tab)

Weber KS, Miller MJ, and Allen PM. (2008) Journal of Immunology. 180(3):1442-1450.

The study of high affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy (opens in a new tab)

Donermeyer DL*, Weber KS*, Kranz DM, and Allen PM. (2006) Journal of Immunology. 177(10):6911-6919. (*co-authors).

Development of a novel strategy for engineering high-affinity proteins by yeast display (opens in a new tab)

Richman SA, Healan SJ, Weber KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, and Kranz DM. (2006) Protein Engineering, Design, and Selection. 19(6):255-264.

Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function (opens in a new tab)

Weber KS, Donermeyer DL, Allen PM, and Kranz DM. (2005)  Proceedings of the National Academy of Sciences. 102(52):19033-19038.

Neurobehavioral effects of dietary soy phytoestrogens (opens in a new tab)

Lephart ED, West TW, Weber KS, Rhees RW, Setchell, KD, Adlercreutz H, and Lund TD.  (2002) Neurotoxicology and Teratology. 24(1), 5-16.

Genetic control of susceptibility to experimental Lyme arthritis is polygenic and exhibits consistent linkage to multiple loci on chromosome 5 in four independent mouse crosses (opens in a new tab)

Roper RJ, Weis JJ, McCracken BA, Green CB, Ma Y, Weber KS, Fairbairn D, Butterfield RJ, Potter MR, Zachary JF, Doerge RW and Teuscher C. (2001) Genes and Immunity. 2 (7), 388-397.

Dietary soy-phytoestrogens decrease testosterone levels and prostate weight, without altering LH, prostate 5a-reductase or testicular StAR levels in adult male Sprague-Dawley rats (opens in a new tab)

Weber KS, Setchell KD, Stocco DM and Lephart ED. (2001) Journal of Endocrinology. 170(3), 591-599.

Maternal and perinatal brain aromatase: Effects of dietary soy phytoestrogens (opens in a new tab)

Weber KS, Setchell KD and Lephart ED. (2001) Developmental Brain Research. 126(2), 217-221.

Neuroendocrine regulation of sexually dimorphic brain structure and associated sexual behavior in male rats is genetically controlled (opens in a new tab)

Lephart ED, Call SB, Rhees RW, Jacobson NA, Weber KS, Bledsoe J and Teuscher C. (2001) Biology of Reproduction. 64(2), 571-578.

Phytoestrogens decrease brain calcium‑binding proteins but do not alter hypothalamic androgen metabolizing enzymes in adult male rats (opens in a new tab)

Lephart ED, Thompson JM, Setchell KD, Adlercreutz H and Weber KS. (2000) Brain Research. 859(1), 123-131.

Brain aromatase and 5 alpha‑reductase, regulatory behaviors and testosterone levels in adult rats on phytoestrogen diets (opens in a new tab)

Weber KS, Jacobson NA, Setchell KD and Lephart ED. (1999) Proceedings of the Society for Experimental Biology and Medicine. 221(2), 131-135.

Calcium signaling in Human Health and Disease - T cell calcium signaling regulation by the CD5 coreceptor (opens in a new tab)

Freitas CMT, Johnson DK, and Weber KS (2019). International Journal of Molecular Sciences, 292-312 doi.org/10.3390/books978-3-03897-538-0

Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic Targeting (opens in a new tab)

Stone JD, Yin Y, Mo M, Weber KS, Donermeyer DL, Allen PM, Mariuzza RA, and Kranz DM. (2012). Protein Engineering, ISBN: 978-953-51-0037-9, InTech.