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College of Life Sciences Microbiology and Molecular Biology
Tessem Laboratory - Diabetes Research Group

Publications

Strat, K. M., T. J. th Rowley, A. T. Smithson, J. S. Tessem, M. W. Hulver, D. Liu, B. M. Davy, K. P. Davy, and A. P. Neilson. "Mechanisms by Which Cocoa Flavanols Improve Metabolic Syndrome and Related Disorders." J Nutr Biochem 35 (Sep 2016): 1-21.

Reynolds, M. S., C. R. Hancock, J. D. Ray, K. B. Kener, C. Draney, K. Garland, J. Hardman, B. T. Bikman, and J. S. Tessem. "Beta-Cell Deletion of Nr4a1 and Nr4a3 Nuclear Receptors Impedes Mitochondrial Respiration and Insulin Secretion." Am J Physiol Endocrinol Metab 311, no. 1 (Jul 1 2016): E186-201.

Ray, J. D., K. B. Kener, B. F. Bitner, B. J. Wright, M. S. Ballard, E. J. Barrett, J. T. Hill, L. G. Moss, and J. S. Tessem. "Nkx6.1-Mediated Insulin Secretion and Beta-Cell Proliferation Is Dependent on Upregulation of C-Fos." FEBS Lett 590, no. 12 (Jun 2016): 1791-803.

Draney, C., A. E. Hobson, S. G. Grover, B. O. Jack, and J. S. Tessem. "Cdk5r1 Overexpression Induces Primary Beta-Cell Proliferation." J Diabetes Res 2016 (2016): 6375804.

Hobson, A., C. Draney, A. Stratford, T. C. Becker, D. Lu, M. Arlotto, and J. S. Tessem. "Aurora Kinase a Is Critical for the Nkx6.1 Mediated Beta-Cell Proliferation Pathway." Islets 7, no. 1 (2015): e1027854.

Tessem, J. S., L. G. Moss, L. C. Chao, M. Arlotto, D. Lu, M. V. Jensen, S. B. Stephens, P. Tontonoz, H. E. Hohmeier, and C. B. Newgard. "Nkx6.1 Regulates Islet Beta-Cell Proliferation Via Nr4a1 and Nr4a3 Nuclear Receptors." Proc Natl Acad Sci U S A 111, no. 14 (Apr 8 2014): 5242-7.

Tessem, J. S., J. N. Jensen, H. Pelli, X. M. Dai, X. H. Zong, E. R. Stanley, J. Jensen, and J. DeGregori. "Critical Roles for Macrophages in Islet Angiogenesis and Maintenance During Pancreatic Degeneration." Diabetes 57, no. 6 (Jun 2008): 1605-17.

Schisler, J. C., P. T. Fueger, D. A. Babu, H. E. Hohmeier, J. S. Tessem, D. Lu, T. C. Becker, B. Naziruddin, M. Levy, R. G. Mirmira, and C. B. Newgard. "Stimulation of Human and Rat Islet Beta-Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1." Mol Cell Biol 28, no. 10 (May 2008): 3465-76.

Tessem, J. S. and J. DeGregori. "Roles for Bone-Marrow-Derived Cells in Beta-Cell Maintenance." Trends Mol Med 10, no. 11 (Nov 2004): 558-64.

Li, F. X., J. W. Zhu, J. S. Tessem, J. Beilke, M. Varella-Garcia, J. Jensen, C. J. Hogan, and J. DeGregori. "The Development of Diabetes in E2f1/E2f2 Mutant Mice Reveals Important Roles for Bone Marrow-Derived Cells in Preventing Islet Cell Loss." Proc Natl Acad Sci U S A 100, no. 22 (Oct 28 2003): 12935-40.